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Invitrogen™ p19 INK4d Monoclonal Antibody (2D2G4)

Description
p19 INK4d Monoclonal Antibody for Western Blot, IP, ELISA
p19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis.
Specifications
Specifications
| Antigen | p19 INK4d |
| Applications | ELISA, Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | 2D2G4 |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.1% sodium azide; pH 7.4 |
| Gene | CDKN2D |
| Gene Accession No. | P55273 |
| Gene Alias | CDK inhibitor p19INK4d; CDK4I; CDKN2D; cell cycle inhibitor, Nur77 associating protein; cyclin dependent kinase inhibitor 2D; cyclin-dependent kinase 4 inhibitor D; cyclin-dependent kinase 4 inhibitor D p19; cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); inhibitor of cyclin-dependent kinase 4d; INK4d; MTS1; p16-INK4; p16-INK4a; p19; p19INK4d; p19-INK4D; similar to cyclin-dependent kinase inhibitor 2D |
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