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  6. Invitrogen™ NME3 Recombinant Rabbit Monoclonal Antibody (K01_2N58)

Invitrogen™ NME3 Recombinant Rabbit Monoclonal Antibody (K01_2N58)
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Product Code. 30828523
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30828523 100 μL
30825064 50 μL
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Product Code. 30828523 Supplier Invitrogen™ Supplier No. MA564142

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: SEELLREHYA ELRE.

NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NME3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone K01_2N58
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 150mM NaCl, 0.05% BSA and 0.01% sodium azide; pH 7.4
Gene NME3
Gene Accession No. Q13232
Gene Alias 1810009F08Rik; AI413736; c371H6.2; DR-nm23; expressed in non-metastatic cells 3; expressed in non-metastatic cells 3 protein (nucleoside diphosphate kinase); expressed in non-metastatic cells 3, protein (nucleoside diphosphate kinase); NDK 3; Ndk3; NDP kinase 3; NDP kinase C; NDPKC; NDPK-C; NM23-dr; NM23H3; nm23-H3; nm23-M3; NME/NM23 nucleoside diphosphate kinase 3; Nme3; non-metastatic cell expressed protein 3; non-metastatic cells 3, protein expressed in; nucleoside diphosphate kinase 3; Nucleoside diphosphate kinase C; nucleoside diphosphate kinase DR-nm23
Gene Symbols NME3
Host Species Rabbit
Immunogen A synthetic peptide of human NME3 (aa 61-74).
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4832
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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