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Invitrogen™ Melanoma Discriminated Antigen Monoclonal Antibody (PAL-M1)

Description
Antibody PAL-M1 stains the majority of primary melanomas and the large majority of metastases and is directed against the transferrin receptor (CD71). Local staining of dysplastic nevocellular nevi may be observed. Common nevocellular nevi rarely stain.
Melanoma is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the rarer types of skin cancer but causes the majority of skin cancer related deaths. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a thickness of greater than 1 mm.
Specifications
Specifications
| Antigen | Melanoma Discriminated Antigen |
| Applications | Flow Cytometry, Immunohistochemistry (Frozen), Western Blot |
| Classification | Monoclonal |
| Clone | PAL-M1 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | tissue culture supernatant with 10mM sodium azide |
| Gene Alias | melanoma antigen; melanoma associated antigen |
| Host Species | Mouse |
| Immunogen | Human melanoma metastases tissue. |
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