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Invitrogen™ LPAM-1 Monoclonal Antibody (DATK32), PE
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Product Code. 10135104
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100 μg
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10135104 100 μg Each
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10135104 Supplier Invitrogen™ Supplier No. MLPAM104

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Rat Monoclonal Antibody

LPAM-1 Monoclonal Antibody for Flow

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
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Specifications

Antigen LPAM-1
Applications Flow Cytometry
Classification Monoclonal
Clone DATK32
Concentration 0.1 mg/mL
Conjugate PE
Formulation PBS with <0.1% sodium azide; pH 7.5
Gene Itgb7
Gene Accession No. P26011, Q00651
Gene Alias CD49 antigen-like family member D; CD49D; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin beta 7; integrin beta-7; Integrin beta-P; Itga4; Itga4B; Itgb7; LPAM subunit alpha; Ly69; lymphocyte Peyer patch adhesion molecules subunit alpha; M290 IEL antigen; VLA; VLA 4; VLA-4 receptor, alpha 4 subunit; VLA4 subunit alpha; VLA-4 subunit alpha
Gene Symbols Itga4, Itgb7
Host Species Rat
Immunogen Mouse LPAM-1.
Purification Method Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16401, 16421
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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