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Invitrogen™ LanthaScreen™ Tb-p4E-BP1 (pThr46) Antibody Kit, 25 μg

Product Code. 10053143
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10053143 25 μg
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10053143 Supplier Invitrogen™ Supplier No. PV4757

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1 upon stimulation of the pathway.

A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1 upon stimulation of the pathway.

For use in combination with the GFP-4E-BP1 physiological protein substrate (Cat. No. PV4759) to evaluate inhibitors in medium to high throughput screening applications. An optimized mTor assay buffer (PV4794) is also available.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Serine/threonine kinase
Applications Kinase Assay, Enzyme and Protein Activity Assays, Kinase Assay
Concentration 0.52mg/mL
Conjugate Tb (Terbium)/GFP (EmGFP)
Molecular Weight of Antigen 150kDa
Quantity 25 μg
Regulatory Status RUO
Research Discipline Target and Lead Identification and Validation
Primary or Secondary Primary
Packaging 1 Kit(s)
Content And Storage Terbium-labeled anti-4E-BP1 [pThr46] antibody in HEPES buffered saline.

Store at -20°C.
Antibody Molecular Weight 150,000 Da
Assay Entry Biochemical terbium phospho-specific activity
Format 384-well Plate
Excitation/Emission 340/490, 520 nm
Reactivity Human
Shipping Condition Dry Ice
Readout End Point
Reactivity abrv Hu
Target Entry mTOR, FRAP1
Target Enzyme Serine/Threonine Kinases
Technique TR-FRET
Validated Kinases FRAP1 (mTOR), FRAP1 (mTOR)
Product Line LanthaScreen
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For Research Use Only. Not for use in diagnostic procedures.

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