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  5. Tocris Bioscience™ INT 131

Tocris Bioscience™ INT 131
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Product Code. 18709696
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18709696 10 mg 10mg
18716706 50 mg 50mg
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Product Code. 18709696 Supplier Tocris Bioscience™ Supplier No. 7423/10

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119.00 GBP valid until 2026-03-31
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Description

PPARγ partial agonist

INT 131 is a potent and selective PPARγ partial agonist (EC50 = 4 nM; Ki = 3.7 nM). It has a 20-fold higher affinity for PPARγ compared with that of Rosiglitazone (Cat. No. 5325). INT 131 improves glucose tolerance in a rodent model of diabetes without inducing hemodynamic and cardiovascular effects. Antidiabetic agent.
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Specifications

Chemical Name or Material 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide
CAS 315224-26-1
Quantity 10 mg
Target PPAR gamma/NR1C3
Molecular Formula C21H12Cl4N2O3S
Purity 0.98
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