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Invitrogen™ IL-4 Polyclonal Antibody
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Product Code. 10127593
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Product Code. 10127593 Supplier Invitrogen™ Supplier No. PBOIL4I

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Description

Rabbit Polyclonal Antibody

PBOIL4I targets IL-4 in ELISA, and WB applications and shows reactivity with Bovine samples. The PBOIL4I immunogen is recombinant bovine IL-4. PBOIL4I detects IL-4 which has a predicted molecular weight of approximately 13 kDa. Endotoxin levels are less than or equal to 10 μg/mL.

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
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Specifications

Antigen IL-4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Il4
Gene Accession No. P30367
Gene Alias B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Gene Symbols Il4
Host Species Rabbit
Immunogen Recombinant bovine IL-4.
Purification Method Protein G
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 280824
Target Species Bovine
Content And Storage 4°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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