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Invitrogen™ IL-13 Polyclonal Antibody

Product Code. 10065883
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1 mg
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Product Code. 10065883 Supplier Invitrogen™ Supplier No. P130E

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Description

Rabbit Polyclonal Antibody

P130E targets IL-13 in ELISA, and WB applications and shows reactivity with Human samples. The P130E immunogen is recombinant human IL-13. P130E detects IL-13 which has a predicted molecular weight of approximately 13 kDa. The P130E IL13 polyclonal antibody has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody M130B (biotinylated conjugate of clone 5A2) Typical dilutions for sandwich ELISA include 1 μg/mL for coating and 0.125 - 0.25 μg/mL for detection. Antibody P130E and biotinylated antibody M130B (clone 5A2) have successfully been used in combination with recombinant IL13 protein SIL13 in ELISA applications.

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-13
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Il13
Gene Accession No. P35225
Gene Alias ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
Gene Symbols Il13
Host Species Rabbit
Immunogen Recombinant human IL-13.
Purification Method Protein A
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3596
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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