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Invitrogen™ IL-10 Monoclonal Antibody (945A1A926C2), Biotin
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Product Code. 10078312
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100 μg
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10078312 100 μg Each
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10078312 Supplier Invitrogen™ Supplier No. ASC9109

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Mouse Monoclonal Antibody

IL-10 Monoclonal Antibody for ELISA

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
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Specifications

Antigen IL-10
Applications ELISA
Classification Monoclonal
Clone 945A1A926C2
Concentration 0.5 mg/mL
Conjugate Biotin
Formulation PBS with 0.1% sodium azide; pH 7.2
Gene IL10
Gene Accession No. Q29055
Gene Alias CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
Gene Symbols IL10
Host Species Mouse
Immunogen Recombinant swine IL-10.
Purification Method Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 397106
Target Species Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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