Gibco™ Human CCL7 (MCP-3) Recombinant Protein

Product Code.	Quantity	unitSize
10039372	10 μg	Each

Product Code. 10039372 Supplier Gibco™ Supplier No. PHC1574

Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. This lyophilized protein should be reconstituted in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in a buffered solution containing carrier protein, such as phosphate buffered saline supplemented with 0.1-1.0% BSA. Storage: This lyophilized preparation is stable at -20°C for up to 2 years from date of receipt. The reconstituted MCP-3 should be apportioned into working aliquots and stored at ≤-20°C for up to 3 months with a carrier protein. Keep freeze-thaw cycles to a minimum.

This is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.

Specifications

• Accession Number: P80098
• For Use With (Application): Bioactivity
• Formulation: Protein with no preservative
• Gene ID (Entrez): 6354
• Molecular Weight (g/mol): 9 kDa
• Name: Human CCL7 (MCP-3)
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <0.1 ng/μg
• Gene Alias: C-C motif chemokine 7; C-C motif chemokine ligand 7; CCL7; chemokine (C-C motif) ligand 7; chemotactic protein-3; Fic; H-MCP-3; Intercrine/chemokine MARC; marc; Mcp3; MCP-3; MGC138463; MGC138465; Monocyte chemoattractant protein 3; monocyte chemotactic protein 3; NC28; Protein FIC; RANTES/sis homolog; RP23-350G1.4; SCYA6; Scya7; small inducible cytokine A7; small inducible cytokine A7 (monocyte chemotactic protein 3); small-inducible cytokine A7
• Common Name: CCL7 (MCP3)
• Gene Symbol: CCL7
• Biological Activity: ED50 = 10 - 100 ng/mL; determined by the dose-dependent chemotaxis of human PBMCs.
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Sequence: Human CCL7 recombinant protein contains 76 amino acids
• Content And Storage: -20°C
• Classification: Carrier-Free
• Activity: ED50 = 10 - 100 ng/mL; determined by the dose-dependent chemotaxis of human PBMCs.
• Endotoxin Level: <0.1 ng/μg
• Shipping Condition: Approved for shipment on Wet or Dry Ice
• Expression System: E. coli
• Protein Family: Chemokines & Receptors
• Protein Form: Recombinant, Ligand
• Form: Lyophilized
• Protein Subtype: MCP⁄MCAF Chemokines
• Research Category: Oncology, Signal Transduction
• Product Line: Gibco
• Purity or Quality Grade: >98% by SDS-PAGE