Invitrogen™ H3K79me3 Polyclonal Antibody

Product Code.	Quantity	unitSize
10054034	50 μg	Each

Product Code. 10054034 Supplier Invitrogen™ Supplier No. 491020

Description

Rabbit Polyclonal Antibody

H3K79me3 Polyclonal Antibody for Western Blot, ELISA, ChIP, ChIP-seq, DB

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

• Antigen: H3K79me3
• Applications: ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.6 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% ProClin 300, 0.05% sodium azide
• Gene: H3C1
• Gene Accession No.: P68431, P68433, P84228, Q71DI3
• Gene Alias: H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K79; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3f3b; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K79; H3Lys79me3; Hist1; Hist1h3a; HIST1H3B; Hist1h3c; Hist1h3d; Hist1h3e; HIST1H3F; Hist1h3g; Hist1h3h; Hist1h3i; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone gene complex 1; histone H3; histone H3.1; Histone H3.2; histone H3.3; Histone H3.3C; histone H3.5; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; histone H3/l; Histone H3/m; histone H3/o; Histone H3K79me3; histone variant H3.5; M32461; methyl Histone 3; methyl Histone H3; PP781; Trimethyl H3; Tri-methyl H3; Trimethyl Histone H3; Tri-methyl Histone H3; Tri-Methyl-H3 K79; Tri-Methyl-H3 Lys79; Tri-Methyl-Histone H3 K79; Tri-Methyl-Histone H3 Lys79
• Gene Symbols: H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7
• Host Species: Rabbit
• Immunogen: raised in rabbits against histone H3 containing the trimethylated lysine 79 [K79me3], using a KLH-conjugated synthetic peptide., using a KLH-conjugated synthetic peptide.
• Purification Method: Affinity chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 126961, 260423, 319150, 319152, 333932, 360198, 8350, 8356, 8357, 8358, 8968, 97114
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG