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H3K4me3 Polyclonal Antibody, Invitrogen™

Product Code. 10083864
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50 μg
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10083864 50 μg Each
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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10083864 Supplier Invitrogen Supplier No. 491005

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Rabbit Polyclonal Antibody

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post tranlationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Tri-Methyl-Histone H3 (Lys4)
Applications ELISA, Immunocytochemistry, Immunofluorescence, Peptide Array, Western Blot
Classification Polyclonal
Concentration 1.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% Proclin 300, 0.05% sodium azide
Gene HIST1H3A
Gene Accession No. P68431, P68433
Gene Alias H3K4me3, Histone H3, Histone 1, H3a, Histone H3.1, histone H3/a, HIST1H3A
Gene Symbols H3c1, HIST1H3A
Host Species Rabbit
Immunogen Raised against the region of the histone H3 containing the trimethylated lysine 4 (or [K4me3]), using a KLH-conjugated synthetic peptide.
Purification Method Affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 360198, 8350
Target Species Human, Multi-species, Mouse, Plant, Zebrafish
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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