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Invitrogen™ FLI1 Polyclonal Antibody
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Product Code. 10058919
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Quantity:
400 μL
Unit Size:
100µg
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Product Code. Quantity unitSize
10058919 400 μL 100µg
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Product Code. 10058919 Supplier Invitrogen™ Supplier No. PA513440

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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, chicken, canine, rat and Xenopus and zebrafish based on sequence homology.

The FLI1 (Friend Leukemia Integration 1) gene is located on chromosome 11q24.3 and belongs to the ETS (E26 transformation-specific) family of transcription factors. Structurally, FLI1 contains an ETS domain responsible for DNA binding and a pointed domain which facilitates protein-protein interactions. Functionally, it plays a critical role in the regulation of embryonic and hematopoietic development. It is also implicated in the pathogenesis of diseases such as Ewing's sarcoma, wherein a chromosomal translocation t(11;22)(q24;q12) forms the EWS-FLI1 fusion gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FLI1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Fli1
Gene Accession No. P26323, Q01543
Gene Alias Ewing sarcoma breakpoint region 2; EWSR2; Fli1; Fli-1; Fli-1 proto-oncogene, ETS transcription factor; Friend leukemia integration 1; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; Retroviral integration site protein Fli-1; Sic1; SIC-1; transcription factor ERGB
Gene Symbols Fli1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 299-328 amino acids from the central region of human FLI1.
Purification Method Size-exclusion - Dialysis, Ammonium sulfate precipitation
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14247, 2313
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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