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  4. Invitrogen™ Human FGR, His Tag Recombinant Protein

Invitrogen™ Human FGR, His Tag Recombinant Protein

Product Code. 10158672
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
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10158672 1 mg 1mg
15440303 100 μg 100µg
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Product Code. 10158672 Supplier Invitrogen™ Supplier No. PV4078

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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

FGR is a SRC-related kinase present in hematopoietic cells. FGR signals within multiple pathways including within the integrin pathway and downstream of chemokine and cytokine receptors. This protein contains N-terminal sites for myristylation and palmitoylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P09769
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 20 mM tris with 0.05% NP-40, 0.05 mM EDTA, 100 mM NaCl, 1 mM DTT, 50% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 2268
Molecular Weight (g/mol) 62 kDa
Name Human FGR, His Tag
Quantity 1 mg
Regulatory Status RUO - research use only
Gene Alias c-fgr; c-fgr protooncogene; c-src2; c-src-2 proto-oncogene; EC 2.7.10.2; feline Gardner-Rasheed sarcoma viral oncogene; feline Gardner-Rasheed sarcoma viral oncogene homolog; FGR; FGR protein; FGR proto-oncogene, Src family tyrosine kinase; FLJ43153; Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; MGC75096; OTTHUMP00000003603; OTTHUMP00000003604; p55c-fgr; p55-c-fgr protein; p55-Fgr; p58c-Fgr; p58-Fgr; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase FGR; SRC2; Tyrosine-protein kinase Fgr; v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog
Common Name FGR
KinaseFamily SRC Kinase Family
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Expression System Insect cells
Form Liquid
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