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Invitrogen™ FGFR1 Monoclonal Antibody (VBS-7)
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Product Code. 10109252
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100 μg
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10109252 100 μg Each
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10109252 Supplier Invitrogen™ Supplier No. 133100

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Mouse Monoclonal Antibody

FGFR1 Monoclonal Antibody for Western Blot, IHC (P), IP, ELISA

FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family that constitute a family of four membrane-spanning tyrosine kinases (FGFR1-4) which serve as high-affinity receptors for 17 growth factors (FGF1-17). The FGF Receptor family plays an important role in multiple biological processes, including mesoderm induction and patterning, cell growth and migration, organ formation and bone growth. FGFR1 is alternatively spliced generating multiple splice variants that are differentially expressed during embryo development and in the adult body. Other defects in FGFR1 are responsible for several diseases which include Pfeiffer syndrome (PS), idiopathic hypogonadotropic hypogonadism (IHH), Kallmann syndrome type 2 (KAL2), osteoglophonic dysplasia (OGD), non-syndromic trigonocephaly, Jackson-Weiss syndrome, Antley-Bixler syndrome. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.
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Specifications

Antigen FGFR1
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone VBS-7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene FGFR1
Gene Accession No. P11362, P16092, P21804, Q04589
Gene Alias 2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; basic fibroblast growth factor receptor I; BFGFR; bFGF-R; bFGF-R-1; CD331; CD331 antigen; CEK; CEK1; cek1 protein; cek1 protein precursor; c-fgr; Eask; ECCL; FGF receptor; FGF receptor-1; FGFBR; FGFR; fgfr 1; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFR1IIIC; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); fibroblast growth factor receptor 1-IIIc; fibroblast growth factor receptor type 1; Flg; FLT2; FLT-2; FMS-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1; MFR; N-sam; OGD; proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1
Gene Symbols FGFR1
Host Species Mouse
Immunogen Bovine FGF Receptor 1 (flg) purified from bovine Coronary Venular Endothelial Cells (CVEC).
Purification Method purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100731156, 14182, 2260, 281768, 396516, 79114
Target Species Human, Mouse, Rat, Bovine, Chicken, Guinea Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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