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Ephrin B1 Monoclonal Antibody (2D3E9), Invitrogen™
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Product Code. 10109062
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100 μg
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10109062 100 μg Each
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10109062 Supplier Invitrogen Supplier No. 378100

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Mouse Monoclonal Antibody

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ephrin B1
Applications ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 2D3E9
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene EFNB1
Gene Accession No. O73612, P98172
Gene Alias CEK5 ligand; CEK5 receptor ligand; CEK5-L; CEL5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; EFNB1; EFNB3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; ephrin B1; Ephrin B3; EphrinB1; ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B1 precursor; Epl2; EPLG2; EPLG8; kinase ephrin-B1; Lerk2; LERK-2; LERK8; Stimulated by retinoic acid gene 1 protein; Stra1; STRA1 protein; transmembrane ligand
Gene Symbols EFNB1
Host Species Mouse
Immunogen Synthetic peptide derived from the ephrin-B sequence.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1947, 395896
Target Species Chicken, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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