Invitrogen™ Desmocollin 2/3 Monoclonal Antibody (7G6)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ 326200

Product Code. 10037612

Description

Desmocollin 2/3 Monoclonal Antibody for IHC (P), IP, Western Blot

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: Desmocollin 2/3
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene Accession No.: Q02487, Q14574
• Gene Symbols: DSC2, DSC3
• Immunogen: Human desmocollin-2 extracellular domain.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 7G6
• Conjugate: Unconjugated
• Gene: DSC3
• Gene Alias: ARVC10; ARVD10; ARVD11; cadherin family member 2; Cadherin family member 3; CDHF2; CDHF3; CDHF5; CDHF6; CMD1BB; desmocollin 2; desmocollin 3; desmocollin-2; Desmocollin-3; desmocollin-4; desmoglein-2; desmoglein-3; Desmosomal glycoprotein II; desmosomal glycoprotein II/III; Desmosomal glycoprotein III; DG2; DGII/III; DSC; DSC1; DSC2; DSC3; DSC4; HDGC; HT-CP; PVA
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1824, 1825
• Content And Storage: -20°C
• Form: Liquid