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  6. Invitrogen™ Cytochrome P450 Reductase Recombinant Mouse Monoclonal Antibody (KBL007_18C12)

Invitrogen™ Cytochrome P450 Reductase Recombinant Mouse Monoclonal Antibody (KBL007_18C12)
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Product Code. 30824753
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30824753 100 μL
30828108 50 μL
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Product Code. 30824753 Supplier Invitrogen™ Supplier No. MA564503

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Description

Mouse Recombinant Monoclonal Antibody

Immunogen sequence: TSSVRESSFV EKMKKTGRNI IVFYGSQTGT AEEFANRLSK DAHRYGMRGM SADPEEYDLA DLSSLPEIDN ALVVFCMATY GEGDPTDNAQ DFYDWLQETD VDLSGVKFAV FGLGNKTYEH FNAMGKYVDK RLEQLGAQRI FELGLGDDDG NLEEDFITWR EQFWPAVCEH FGVEATGEES SIRQYELVVH Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%, Pig - 93%, Cynomolgus monkey - 100%.

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytochrome P450 Reductase
Applications Western Blot
Classification Recombinant Monoclonal
Clone KBL007_18C12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene POR
Gene Accession No. P16435
Gene Alias 4933424M13Rik; CCR; CPR; CY DKFZp686G04235; CYPOR; cytochrome p450 oxidoreductase; cytochrome P450 reductase; DKFZp686G04235; FLJ26468; I79_007261; LOC101115252; NADPH Cytochrome; NADPH-cytochrome P450 oxidoreductase; NADPH-cytochrome P-450 oxidoreductase; NADPH-cytochrome P450 reductase; NADPH--cytochrome P450 reductase; NADPH-cytochrome P-450 reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450 Reductase; P450R; Por; unnamed protein product
Gene Symbols POR
Host Species Mouse
Immunogen Recombinant human POR (aa 61-250).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5447
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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