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Invitrogen™ CDKL5 Polyclonal Antibody

Description
CDKL5 Polyclonal Antibody for Western Blot, IHC (P)
CDKL5 serine/threonine kinase (STK9) is associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome and Rett syndrome (RTT). CDKL5 can control nuclear speckle morphology by regulating the phosphorylation state of splicing regulatory proteins, and may be involved indirectly in pre-mRNA processing by controlling splicing factor dynamics. The mutations in CDKL5 are major cause of infantile spasms and early epileptic seizures in female patients, and of a later intractable seizure disorder.
Specifications
Specifications
| Antigen | CDKL5 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.09% sodium azide; pH 7.4 |
| Gene | CDKL5 |
| Gene Accession No. | O76039 |
| Gene Alias | BC038161; Cdkl5; CFAP247; cyclin dependent kinase 5 transcript; cyclin dependent kinase like 5; cyclin-dependent kinase-like 5; EIEE2; ISSX; RP1-245G19.3; serine/threonine kinase 9; serine/threonine-protein kinase 9; STK9 |
| Gene Symbols | CDKL5 |
| Show More |
Product Title
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