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CDK7/Cyclin H/MNAT1 Recombinant Human Protein

CDK7/Cyclin H/MNAT1 Recombinant Human Protein

Brand:  Invitrogen PV4186

Code : NEW

Additional Details : Weight : 0.00001kg

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Product Code. 10046842

  • £4980.00 / 1mg

Estimated Shipment date
from Supplier 09-01-2020

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Description

Description

The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Specifications

Specifications

NP_001790, Q130R, NP_001230, NP_002422
Protein assays and analysis
Frozen
CDK7/Cyclin H/MNAT1 Recombinant Human Protein
1mg
For research use only. Not for use in diagnostic procedures
CDK7/Cyclin H/MNAT1
CDK7/cyclin H/MNAT1 was pre-diluted in enzyme dilution buffer and assayed in 12.5mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 333μg/mL CDK7/9tide peptide substrate (YSPTSPSYSPTSPSYSPTSPSKKKK) and trace [32P]-γ-ATP for 10 minutes at 30°C
Baculovirus
CDK7/cyclin H/MNAT1 Recombinant Human Protein
Human
0.4mg/mL
Frozen
126.3kDa
70% by SDS-PAGE
–80°C
1 Each
CDK7/Cyclin H/MNAT1 Recombinant Human Protein
Kinase assay
CDK and CHK
96nmoles of phosphate transferred to CDK7/9tide peptide substrate (YSPTSPSYSPTSPSYSPTSPSKKKK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 3.33μg/mL
His Tag
Videos
Documents

For Research Use Only. Not for use in diagnostic procedures.