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Invitrogen™ CD49a Monoclonal Antibody (TS2/7)
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Product Code. 10127643
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Quantity:
100 Tests
Unit Size:
100 tests
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10127643 100 Tests 100 tests
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Product Code. 10127643 Supplier Invitrogen™ Supplier No. MA49A0

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Description

Mouse Monoclonal Antibody

MA49A0 targets CD49a in FACS, IHC(F), IP, and WB applications and shows reactivity with Human samples. The MA49A0 immunogen is human VLA-1 antigen. MA49A0 detects CD49a which has a predicted molecular weight of approximately 128 kDa.

Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49a
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone TS2/7
Concentration 20 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA and 0.1% sodium azide
Gene Itga1
Gene Accession No. P56199
Gene Alias CD49 antigen-like family member A; CD49a; E130012M19Rik; integrin alpha 1; integrin alpha-1; integrin subunit alpha 1; integrin, alpha 1; Itga1; Laminin and collagen receptor; very late activation protein 1; Vla1; VLA-1
Gene Symbols Itga1
Host Species Mouse
Immunogen Human VLA-1 antigen.
Purification Method Protein G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3672
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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