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  6. Invitrogen™ CD31 Monoclonal Antibody (MBC78.2), FITC

Invitrogen™ CD31 Monoclonal Antibody (MBC78.2), FITC
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Product Code. 10671244
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Quantity:
500 μL
2 mL
Unit Size:
Each
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Product Code. Quantity unitSize
10671244 500 μL Each
10028632 2 mL Each
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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10671244 Supplier Invitrogen™ Supplier No. MHCD3101

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Mouse Monoclonal Antibody

Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD31
Applications Flow Cytometry
Classification Monoclonal
Clone MBC78.2
Concentration 0.2mg/mL
Conjugate FITC
Description CD31 Monoclonal Antibody, 0.5mL, 0.2mg/mL Concentration, MBC78.2 Clone, CD31 Antigen, Human CD31 Immunogen, Mouse Host, Human Species Reactivity, FITC Conjugate, IgG1 Isotype, PBS + BSA Storage Buffer, Used for Flow Cytometry
Dilution Assay-dependent
Formulation PBS with 4mg/mL BSA and 0.1% sodium azide
Gene Pecam1
Gene Accession No. P16284
Gene Alias C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Gene Symbols Pecam1
Host Species Mouse
Immunogen Human CD31.
Purification Method Purified
Quantity 500 μL
Regulatory Status ASR
Primary or Secondary Primary
Gene ID (Entrez) 5175
Packaging 1 Each
Includes 0.1% Sodium azide
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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