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CD11b, FITC, clone: VIM12, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen CD11B014

Code : 50

Additional Details : Weight : 0.50000kg

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Product Code. 10180273

  • £572.00 / Each
Estimated Shipment: 31-08-2022
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For Research Use Only. All usage must comply with product instructions.
 

Description

Description

CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X, and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, and blood monocytes. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue.

Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.
Specifications

Specifications

CD11b
Monoclonal
FITC
ITGAM
CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6, Integrin alpha M
Mouse
Purified
ASR, ASR/IVD
3684
Store at 2 - 8 °C.
Liquid
Flow Cytometry
VIM12
PBS with BSA and 0.1% sodium azide
P11215
ITGAM
Human CD11b (Mac-1)
2 mL
Primary
Human
Antibody
IgG1
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