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Invitrogen™ c-Jun Monoclonal Antibody (ZC008)

Description
c-Jun Monoclonal Antibody for Western Blot, ICC/IF, ELISA
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
Specifications
Specifications
| Antigen | c-Jun |
| Applications | ELISA, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | ZC008 |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.1% sodium azide; pH 7.4 |
| Gene | JUN |
| Gene Accession No. | P05412, P05627 |
| Gene Alias | Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog |
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