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  5. Tocris Bioscience™ AZD 8055

Tocris Bioscience™ AZD 8055
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Product Code. 30000027
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Product Code. 30000027 Supplier Tocris Bioscience™ Supplier No. 7840/50

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Description

Highly potent and selective mTOR inhibitor

AZD 8055 is a highly potent, selective and ATP-competitive mTOR inhibitor (IC50 = 0.8 nM). Inhibits growth and induces autophagy in a range of cancer cell lines and xenografts, including NSCLC and glioblastoma (IC50 values are 20, 50 and 53 nM in H838, A549 and U87MG cell lines, respectively). Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
CAS 1009298-09-2
Quantity 50 mg
Target mTOR Inhibitors
Molecular Formula C25H31N5O4
Purity 0.98
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