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Apremilast, MedChemExpress
Description
Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM.
Specifications
Specifications
| Chemical Name or Material | Apremilast |
| CAS | 608141-41-9 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C22H24N2O7S |
| Quantity | 10 mg |
| Synonym | CC-10004 |
| Solubility Information | DMSO : 44 mg/mL (95.55 mM; Need ultrasonic) |
| SMILES | CC(NC1=CC=CC(C(N2[C@@H](C3=CC=C(OC)C(OCC)=C3)CS(=O)(C)=O)=O)=C1C2=O)=O |
| Molecular Weight (g/mol) | 460.5 |
| Show More |
Research purposes only
Product Title
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