CD24 Rat anti-Mouse, Unlabeled, Clone: J11D, BD

Product Code.	Quantity	unitSize
10126514	0.5 mg	Each

Product Code. 10126514 Supplier BD Biosciences Supplier No. 553146

Description

Rat Monoclonal Antibody

The J11d antibody reacts with CD24 (Heat Stable Antigen, HSA or HsAg), a variably glycosylated membrane protein found on erythrocytes, granulocytes, monocytes, and lymphocytes. Levels of expression of CD24 vary during differentiation of the T and B cell lineages: Immature B cells in the bone marrow and spleen of adult mice express high levels of CD24, whereas mature peripheral B cells express intermediate levels of CD24. Similarly, the majority of thymocytes express high levels of CD24, while mature thymic and peripheral T cells do not express CD24. Dendritic cells of the thymus, spleen, liver, and epidermal Langerhans cells have also been reported to express CD24. CD24 is not expressed by NK cells. CD24 is a ligand of CD62P (P-selectin). In vitro treatment of splenocytes with J11d antibody plus complement reduces primary IgM responses and proliferative responses to LPS. While the monoclonal antibodies 30-F1 (Cat. no. 558777), M1/69 (Cat. no. 557436), and J11d all react with CD24, they show subtle differences in the level of staining of different cell populations. When possible, investigators should continue to use the same monoclonal antibody as used in previous studies.

Specifications

• Antigen: CD24
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: J11D
• Concentration: 0.5mg/mL
• Conjugate: Unconjugated
• Description: Heat Stable Antigen
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Rat
• Immunogen: C3H/HeJ mouse thymocytes
• Purification Method: Affinity Purified
• Quantity: 0.5 mg
• Regulatory Status: RUO
• Research Discipline: Immunology
• Primary or Secondary: Primary
• Target Species: Mouse
• Content And Storage: Store undiluted at 4°C
• Isotype: IgM κ

For Research Use Only.