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  6. CD184 Mouse anti-Human, APC, Clone: 12G5, BD

CD184 Mouse anti-Human, APC, Clone: 12G5, BD

Product Code. 10107913
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25 Tests
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10107913 100 Tests Each
15800619 25 Tests Each
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Product Code. 10107913 Supplier BD Biosciences Supplier No. 555976

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Description

Mouse Monoclonal Antibody

Reacts with fusin (CXCR4), a seven-transmembrane domain, G-protein-linked glycoprotein. Fusin is expressed on a wide variety of CD4+ and CD4- cells including those from spleen, brain and lung. It has been shown to function as a cofactor for infection with T-cell tropic strains of HIV-1 and also as a receptor for CD4-independent infection. 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.

Host Species: Mouse
Clone: 12G5
Isotype: IgG2a κ
Species Reactivity: Human

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD184
Applications Flow Cytometry
Classification Monoclonal
Clone 12G5
Conjugate APC
Description CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen SIVmac variant CP-MAC-infected Sup-T1 cells
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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