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A2M Mouse anti-Human, Clone: 2D9, Invitrogen™

Product Code. 10151080
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Quantity:
100 μL
Unit Size:
100µg
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10151080 100 μL 100µg
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Product Code. 10151080 Supplier Invitrogen Supplier No. LFMA0137

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Description

Mouse Monoclonal Antibody

A suggested positive control for this product is human plasma.

Alpha 2-Macroglobulin (a2M), is a ∽720-kDa homotetrameric glycoprotein composed of four identical ∽180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregcy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer′s disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.
TRUSTED_SUSTAINABILITY

Specifications

Antigen A2M
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2D9
Conjugate Unconjugated
Gene A2M
Gene Accession No. P01023
Gene Alias CPAMD5, DKFZp779B086, FWP007, S863-7
Gene Symbols A2M
Host Species Mouse
Immunogen Alpha 2-macroglobulin purified from human plasma.
Purification Method Ammonium sulfate precipitation
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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