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Invitrogen™ Annexin A1 Polyclonal Antibody

Description
This antibody is specific for the Annexin I protein and does not cross-react with other Annexins.Reactivity with Annexin I was confirmed by western blotting using total lysates derived from human fibroblasts. Positive control lysates used: human fibroblasts, mouse kidney, mouse lung, adult rat and mouse brain.
Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
Specifications
Specifications
| Antigen | Annexin A1 |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | Whole serum with 0.1% sodium azide |
| Gene | ANXA1 |
| Gene Accession No. | P04083, P07150, P10107 |
| Gene Alias | ANAX1; Annexin 1 (p35) (Lipocortin 1); annexin A1; Annexin I; annexin I (lipocortin I); annexin-1; ANX1; Anx-1; Anxa1; Anx-A1; C430014K04Rik; Calpactin II; calpactin-2; Chromobindin-9; lipocortin 1; lipocortin I; LPC1; Lpc-1; p35; Phospholipase A2 inhibitory protein; RP11-71A24.1 |
| Gene Symbols | ANXA1 |
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