Invitrogen™ ALK Recombinant Human Protein

Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily.

Brand:  Invitrogen™ PV4185

Product Code. 10188492

Description

ALK is vital for brain development. Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors, including anaplastic large cell lymphoma, neurblastoma, and non-small cell lung cancer. Chromosomal rearrangement is the most common genetic alteration.

Specifications

• Accession Number: NP_004295
• Validated Application: Kinase Assay
• Formulation: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
• Molecular Weight: 89.9kDa
• Storage Requirements: Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
• Gene Alias: CD246, NBLST3
• Host Species: Human
• Protein Tag: GST Tag

• Expression System: Baculovirus
• For Use With (Application): Target & Lead Identification & Validation, Kinase Biology, Kinase Proteins & Expression Reagents, Protein Biology, Enzyme & Protein Activity Assays, Kinase Activity, Protein Assays and Analysis, Industrial & Applied Science, Pharma & Biopharma
• Gene ID (Entrez): 238
• Quantity: 1mg
• Structural Form: Active
• KinaseFamily: ALK Kinase Family
• Recombinant: Yes