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Invitrogen™ AGTR2 Polyclonal Antibody
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Product Code. 10008539
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Quantity:
100 μL
Unit Size:
100µL
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10008539 100 μL 100µL
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Product Code. 10008539 Supplier Invitrogen™ Supplier No. PA3210

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Description

Rabbit Polyclonal Antibody

PA3-210 detects AGTR2 in human samples. PA3-210 has successfully been used in Western blot, immunocytochemical, and immunohistochemical (paraffin) procedures. The PA3-210 immunogen is a synthetic peptide corresponding to the C-terminal amino acids C(349)RKSSSLREMETFVS(363) of AGTR2.

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AGTR2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with 0.02% sodium azide
Gene Agtr2
Gene Accession No. P50052
Gene Alias AGTR2; AI316812; Angiotensin ii at2; angiotensin II receptor type 2; angiotensin II receptor, type 2; angiotensin II type 2 receptor; angiotensin II type-2 receptor; angiotensin receptor 2; AT>sub>2>/sub>R; AT2; AT2 receptor; AT2R; AT2-R; ATGR2; AW107640; MRX88; type-2 angiotensin II receptor
Gene Symbols Agtr2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the C-terminal amino acids C(349)RKSSSLREMETFVS(363) of AGTR2.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 186
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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