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Invitrogen™ Acetylcholinesterase Monoclonal Antibody (HR2)
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Product Code. 10122194
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Quantity:
200 μL
Unit Size:
200µL
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10122194 200 μL 200µL
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Product Code. 10122194 Supplier Invitrogen™ Supplier No. MA3042

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Description

Mouse Monoclonal Antibody

MA3-042 detects acetylcholinesterase (AChE) from human, mouse, rabbit, guinea pig, bovine and cat tissues. This antibody does not cross react with rat or frog AChE, and does not detect butyrylcholinesterase (BChE). MA3-042 has been successfully used in immunohistochemistry, immunoprecipitation and ELISA procedures. This antibody cannot be used in Western blot to detect AChE. Immunohistochemical staining of AChE in human brain samples with MA3-042 results in staining of nerve fibers and terminals. The MA3-042 antigen is purified human cerebellar acetylcholinesterase.

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Acetylcholinesterase
Applications ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry
Classification Monoclonal
Clone HR2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene ACHE
Gene Accession No. O62763, P21836, P22303, P23795
Gene Alias ACE-1; ACEE; Acetylcholinesterase; acetylcholinesterase (Cartwright blood group); acetylcholinesterase (Yt blood group); acetylcholinesterase T-subunit; ACHE; ache protein; apoptosis-related acetylcholinesterase; ARACHE; EC 3.1.1.7; glycolipid-anchored form of acetylcholinesterase; N-ACHE; OTTHUMP00000211349; OTTHUMP00000211356; YT; Yt blood group; zgc:92550; ziehharmonika; zim
Gene Symbols ACE-1, ACHE
Host Species Mouse
Immunogen Purified human cerebellar acetylcholinesterase.
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009390, 100422792, 11423, 43, 493674, 540446
Target Species Human, Mouse, Rabbit, Bovine, Feline, Guinea Pig
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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