Invitrogen™ Human ABL2 (Arg), His Tag Recombinant Protein

Product Code.	Quantity	unitSize
10104852	1 mg	1mg
11553407	10 μg	10µg

Product Code. 10104852 Supplier Invitrogen™ Supplier No. PV3586

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length

ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization. Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. Abl2 is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Specifications

• Accession Number: P42684
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50 mM tris with 0.05% NP-40, 200 mM NaCl, 2 mM EDTA, 50% glycerol, 5 mM DTT and no preservative; pH 7.5
• Gene ID (Entrez): 27
• Molecular Weight (g/mol): 130.9 kDa
• Name: Human ABL2 (Arg), His Tag
• Quantity: 1 mg
• Regulatory Status: For research use only. Not for use in diagnostic procedures
• Gene Alias: AA536808; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; ABL proto-oncogene 2, non-receptor tyrosine kinase; Abl1-related gene product; abl2; ABLL; ARG; arg tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; FLJ22224; FLJ31718; FLJ41441; tyrosine kinase ARG; tyrosine-protein kinase ABL2; Tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
• Common Name: Abl2
• KinaseFamily: ABL
• Product Type: ABL2 (Arg) Recombinant Human Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Expression System: Insect cells
• Form: Liquid
• Purity or Quality Grade: 65% by SDS-PAGE