Invitrogen™ 4EBP1 Monoclonal Antibody (554R16)

Product Code.	Quantity	unitSize
10037712	100 μg	Each

Product Code. 10037712 Supplier Invitrogen™ Supplier No. AHO1382

Description

Mouse Monoclonal Antibody

4EBP1 Monoclonal Antibody for Western Blot, ICC/IF

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Spécification

• Antigen: 4EBP1
• Applications: Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 554R16
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
• Gene: EIF4EBP1
• Gene Accession No.: Q13541, Q60876, Q62622
• Gene Alias: 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
• Gene Symbols: EIF4EBP1
• Host Species: Mouse
• Immunogen: Recombinant human 4E-BP1 protein expressed in E. coli.
• Purification Method: purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 116636, 13685, 1978
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ