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CAS RN 955365-80-7

CAS RN 955365-80-7

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1

MK 1775, TRC

CAS: 955365-80-7 Molecular Formula: C27H32N8O2 Molecular Weight (g/mol): 500.6 Synonym: Adavosertib,MK-1775,MK 1775 SMILES: CN1CCN(CC1)c2ccc(Nc3ncc4C(=O)N(CC=C)N(c5cccc(n5)C(C)(C)O)c4n3)cc2

CAS 955365-80-7
Molecular Weight (g/mol) 500.6
SMILES CN1CCN(CC1)c2ccc(Nc3ncc4C(=O)N(CC=C)N(c5cccc(n5)C(C)(C)O)c4n3)cc2
Synonym Adavosertib,MK-1775,MK 1775
Molecular Formula C27H32N8O2
2
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Tocris Bioscience™ Adavosertib
GREENER_CHOICE

Potent and selective Wee1 inhibitor

Target Checkpoint Control Kinase Inhibitors
CAS 955365-80-7
Purity 98%
Chemical Name or Material 1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3 H-pyrazolo[3,4-d]pyrimidin-3-one
Recommended Storage Store at -20°C
Molecular Formula C27H32N8O2
3

Adavosertib, MedChemExpress

MedChemExpress Adavosertib (AZD-1775; MK-1775) is a potent Wee1 inhibitor with an IC50 of 5.2 nM.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 500.6
Color Yellow
Physical Form Solid
Chemical Name or Material Adavosertib
Grade Research
SMILES O=C1N(N(C2=NC(NC3=CC=C(C=C3)N4CCN(CC4)C)=NC=C21)C5=NC(C(O)(C)C)=CC=C5)CC=C
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.59%
CAS 955365-80-7
Solubility Information DMSO : 125 mg/mL (249.70 mM; Need ultrasonic)
Health Hazard 1 H315∣H319∣H335
Synonym AZD1775 MK-1775
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C27H32N8O2
Formula Weight 500.6