CAS RN 865305-30-2

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AF-353, MedChemExpress

MedChemExpress AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3.

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Specifications

Molecular Weight (g/mol)	400.21
Color	Brown
Physical Form	Solid
Chemical Name or Material	AF-353
Grade	Research
SMILES	CC(C)C1=C(OC2=CN=C(N)N=C2N)C=C(I)C(OC)=C1
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.0%
CAS	865305-30-2
Solubility Information	DMSO : 100 mg/mL (249.87 mM; Need ultrasonic)
Synonym	Ro-4
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₄H₁₇IN₄O₂
Formula Weight	400.21

CAS RN 865305-30-2

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