CAS RN 848354-66-5
CAS RN 848354-66-5
IUPAC Name:
7-[(2-methylpropanoyl)sulfanyl]-N-(4-phenyl-1,3-thiazol-2-yl)heptanamide
Synonyms:
7-[(2-methylpropanoyl)sulfanyl]-N-(4-phenyl-1,3-thiazol-2-yl)heptanamide
Molecular Weight (g/mol):
390.56
Molecular Formula:
C20H26N2O2S2
InChi Key:
MDYDGUOQFUQOGE-UHFFFAOYSA-N
SMILES:
CC(C)C(=O)SCCCCCCC(=O)NC1=NC(=CS1)C1=CC=CC=C1
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PTACH, MedChemExpress
MedChemExpress PTACH (NCH-51) is a potent HDAC inhibitor with IC50s of 48 nM, 32 nM, and 41 nM for HDAC1, HDAC4, and HDAC6, respectively. PTACH exerts potent growth inhibition against various cancer cells (EC50s of 1.1-9.1 μM) .