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CAS RN 2411853-34-2

CAS RN 2411853-34-2

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JR-AB2-011, MedChemExpress

MedChemExpress JR-AB2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 μM. JR-AB2-011 inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 μM). JR-AB2-011 has anti-glioblastoma multiforme (GBM) properties.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 398.28
Color White
Physical Form Solid
Chemical Name or Material JR-AB2-011
Grade Research
SMILES ClC1=C(Cl)C=C(NC(N2/C(SC(C)C2)=N/C3=CC=C(F)C=C3)=O)C=C1
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.09%
CAS 2411853-34-2
Solubility Information DMSO : 62.5 mg/mL (156.92 mM; Need ultrasonic)
Purity Grade Notes Research
Recommended Storage 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula C17H14Cl2FN3OS
Formula Weight 398.28