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CAS RN 1301214-47-0

CAS RN 1301214-47-0

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Tocris Bioscience™ PF 05175157
GREENER_CHOICE

Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor

Target Additional Lipid Metabolism Compounds
CAS 1301214-47-0
Purity >98%
Chemical Name or Material 1,4-Dihydro-1′-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one
Recommended Storage Store at 4°C
Molecular Formula C23H27N5O2
Formula Weight 405.49
2

PF-05175157, MedChemExpress

MedChemExpress PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 405.49
Color White
Physical Form Solid
Chemical Name or Material PF-05175157
Grade Research
SMILES O=C1CC2(CCN(C(C3=CC=C4C(NC(C)=N4)=C3)=O)CC2)CC5=C1N(C(C)C)N=C5
For Use With (Application) Metabolism-sugar/lipid metabolism
Percent Purity 96.13%
CAS 1301214-47-0
Solubility Information DMSO : 30 mg/mL (73.98 mM; Need ultrasonic and warming)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C23H27N5O2
Formula Weight 405.49