CAS RN 1269662-73-8

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MedChemExpress Pyrotinib (SHR-1258) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively.

Molecular Weight (g/mol)	583.08
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Pyrotinib
Grade	Research
SMILES	O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/[C@@H]5N(C)CCC5
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.84%
CAS	1269662-73-8
Solubility Information	DMSO : 10 mg/mL (17.15 mM; ultrasonic and adjust pH to 6 with HCl)
Synonym	SHR-1258
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₂H₃₁ClN₆O₃
Formula Weight	583.08