CAS RN 1214265-56-1

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WZ-3146, MedChemExpress

MedChemExpress WZ3146 is a mutant selective EGFR inhibitor with IC50s of 2, 2, 5, 14 and 66 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750, EGFRE746_A750/T790M and EGFR, respectively.

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Molecular Weight (g/mol)	464.95
Color	Off-White
Physical Form	Powder
Chemical Name or Material	WZ-3146
Grade	Research
SMILES	CN1CCN(C2=CC=C(C=C2)NC3=NC=C(C(OC4=CC(NC(C=C)=O)=CC=C4)=N3)Cl)CC1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.11%
CAS	1214265-56-1
Solubility Information	DMSO : 62.5 mg/mL (134.42 mM; ultrasonic and warming and heat to 60°C)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₅ClN₆O₂
Formula Weight	464.95

CAS RN 1214265-56-1

CAS RN 1214265-56-1

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