CAS RN 1020149-73-8

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SGI-1027, MedChemExpress

MedChemExpress SGI-1027 is a DNA methyltransferase (DNMT) inhibitor, with IC50s of 7.5 μM, 8 μM, and 12.5 μM for DNMT3B, DNMT3A, and DNMT1 with poly(dI-dC) as substrate.

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Specifications

Molecular Weight (g/mol)	461.52
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	SGI-1027
Grade	Research
SMILES	O=C(NC1=CC=C(NC2=NC(N)=NC(C)=C2)C=C1)C3=CC=C(NC4=CC=NC5=CC=CC=C45)C=C3
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.35%
CAS	1020149-73-8
Solubility Information	DMSO : 27 mg/mL (58.50 mM; Need ultrasonic and warming)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₂₃N₇O
Formula Weight	461.52

CAS RN 1020149-73-8

CAS RN 1020149-73-8

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