CAS RN 1015787-98-0

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Gefapixant, MedChemExpress

MedChemExpress Gefapixant is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ∼30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis.

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Specifications

Molecular Weight (g/mol)	353.4
Color	White
Physical Form	Solid
Chemical Name or Material	Gefapixant
Grade	Research
SMILES	O=S(C1=CC(OC2=CN=C(N)N=C2N)=C(C(C)C)C=C1OC)(N)=O
For Use With (Application)	COVID-19-anti-virus
Percent Purity	98.01%
CAS	1015787-98-0
Solubility Information	DMSO : 5 mg/mL (14.15 mM; ultrasonic and adjust pH to 5-6 with HCl)
Synonym	MK-7264 AF-219
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₄H₁₉N₅O₄S
Formula Weight	353.4

CAS RN 1015787-98-0

CAS RN 1015787-98-0

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