A collection of genes utilized by the RNA interference (RNAi) pathway; the RNAi pathway is a biological process in which RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules. Ideal for genetic screening.
Targets 1,817 genes with up to 4 gRNA per gene target for a total of 7,268 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus
Targets 510 genes commonly involved in the development of cancer with up to 4 gRNA per gene target for a total of 2,040 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
Targets 396 genes with up to 4 gRNA per gene target for a total of 1,548 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus
Targets 822 genes with up to 4 gRNA per gene target for a total of 3,288 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
The Silencer™ Select Human Cancer Genome siRNA Library contains 1596 Invitrogen™ Silencer Select siRNAs targeting 532 gene targets that are commonly affected in cancers.
The Invitrogen™ LentiArray™ Human Cell Surface Protein Library targets 778 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 3,112 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
Mutations that cause a loss or reduction in gene function can result in the progression to cancer, usually in combination with other genetic changes. Tumor suppressor genes, or anti-oncogenes, can protect cells on the path to becoming cancerous.