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Dioxolanes

Organic heterocyclic compounds that consist of a five-membered ring with two oxygen atoms and three carbon atoms.

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1

BTZ043, MedChemExpress

MedChemExpress BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), with MICs of of 2.3 nM and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 431.39
Color Yellow
Physical Form Solid
Chemical Name or Material BTZ043
Grade Research
SMILES O=C1N=C(N(CC2)CCC32OC[C@H](C)O3)SC4=C([N+]([O-])=O)C=C(C(F)(F)F)C=C14
For Use With (Application) Cancer-programmed cell death
Percent Purity 99.75%
CAS 1161233-85-7
Solubility Information DMSO : 13.3 mg/mL (30.83 mM; Need ultrasonic and warming)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C17H16F3N3O5S
Formula Weight 431.39
2

Topiramate, MedChemExpress

MedChemExpress Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 339.36
Color White
Physical Form Solid
Chemical Name or Material Topiramate
Grade Research
SMILES NS(OC[C@]1(OC(C)(C)O2)[C@@H]2[C@H](OC(C)(C)O3)[C@H]3CO1)(=O)=O
For Use With (Application) Neuroscience-Neuromodulation
Percent Purity 98.0%
CAS 97240-79-4
Solubility Information DMSO : ≥ 100 mg/mL (294.67 mM) ∣H2O : 4 mg/mL (11.79 mM; Need ultrasonic)
Health Hazard 1 H315∣H319∣H335
Synonym McN 4853 RWJ 17021
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C12H21NO8S
Formula Weight 339.36