A collection of genes utilized by the RNA interference (RNAi) pathway; the RNAi pathway is a biological process in which RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules. Ideal for genetic screening.
Targets 475 genes with up to 4 gRNA per gene target for a total of 1,900 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
The Silencer™ Select Human Ubiquitin siRNA Library contains 2,943 Invitrogen™ Silencer Select siRNA s targeting 981 genes, including ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin ligases.
The Silencer Human Drug Targets siRNA Library contains 23,745 Invitrogen™ Silencer siRNAs targeting 7,915 genes for performing RNAi screens against known human drug target genes.
The Invitrogen™ LentiArray™ Human Cancer Biology Library targets 510 genes commonly involved in the development of cancer with up to 4 gRNA per gene target (pooled in a single well) for a total of 2,040 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
The Silencer™ Human DNA Damage Response siRNA Library contains 1,725 Invitrogen™ Silencer siRNAs targeting 575 genes for performing RNAi screens against known DNA damage response pathways.
The Silencer Human Transcription Factor siRNA Library targets genes expressing proteins that bind DNA in a sequence-specific manner to control the rate of transcription of genetic information from DNA to messenger RNA.
Targets 716 genes with up to 4 gRNA per gene target for a total of 2,864 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus
Targets 778 genes with up to 4 gRNA per gene target for a total of 3,112 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus
The Silencer Human Drug Targets siRNA Library contains 23,745 Invitrogen™ Silencer siRNAs targeting 7,915 genes for performing RNAi screens against known human drug target genes.
Targets 141 genes with up to 4 gRNA per gene target for a total of 564 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus