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ZM 323881 hydrochloride, Tocris Bioscience™

Potent, selective inhibitor of VEGFR-2

Brand:  Tocris (Bio-Techne) 247510

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13431294

  • £260.19 / 10mg

Estimated Shipment date
from Supplier 27-03-2020

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Description

Description

Potent and selective inhibitor of human vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) activity. Selectively inhibits VEGFR-2 (IC50 = 2 nM) over VEGFR-1 and a range of other receptor tyrosine kinases such as PDGFRβ, FGFR1, EGFR and erbB2 (IC50 > 50 μM). Inhibits VEGF-A-induced endothelial cell proliferation in vitro (IC50 = 8 nM).
Specifications

Chemical Identifiers

193000-39-4
411.861
zm 323881 hydrochloride, zm323881 hydrochloride, zm-323881 hydrochloride, 5-7-benzyloxyquinazolin-4-yl amino-4-fluoro-2-methylphenol hydrochloride, 5-7-benzyloxy quinazolin-4-yl amino-4-fluoro-2-methylphenol hydrochloride, zm 323881 monohydrochloride, zm-323881 monohydrochloride, 5-7-benzyloxy quinazolin-4-ylamino-4-fluoro-2-methylphenol hydrochloride
4-fluoro-2-methyl-5-[(7-phenylmethoxyquinazolin-4-yl)amino]phenol;hydrochloride
C22H19ClFN3O2
AVRHWGLIYGJSOD-UHFFFAOYSA-N
22624897
CC1=CC(=C(C=C1O)NC2=NC=NC3=C2C=CC(=C3)OCC4=CC=CC=C4)F.Cl

Specifications

10mg
193000-39-4
zm 323881 hydrochloride, zm323881 hydrochloride, zm-323881 hydrochloride, 5-7-benzyloxyquinazolin-4-yl amino-4-fluoro-2-methylphenol hydrochloride, 5-7-benzyloxy quinazolin-4-yl amino-4-fluoro-2-methylphenol hydrochloride, zm 323881 monohydrochloride, zm-323881 monohydrochloride, 5-7-benzyloxy quinazolin-4-ylamino-4-fluoro-2-methylphenol hydrochloride
CC1=CC(=C(C=C1O)NC2=NC=NC3=C2C=CC(=C3)OCC4=CC=CC=C4)F.Cl
411.861
411.86
ZM 323881 hydrochloride
C22H19ClFN3O2
AVRHWGLIYGJSOD-UHFFFAOYSA-N
4-fluoro-2-methyl-5-[(7-phenylmethoxyquinazolin-4-yl)amino]phenol;hydrochloride
22624897
>99%
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