ZK 756326, Tocris Bioscience™

Selective, non-peptide CCR8 agonist

Brand:  Tocris (Bio-Techne) 256550

Product Code. 13461484

Description

Selective, non-peptide CCR8 chemokine receptor agonist (IC50 values are 1.8 and 2.6 μM for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.

Chemical Identifiers

• Chemical Name or Material: ZK 756326
• Molecular Formula: C₂₁H₂₈N₂O₃·2HCl
• Formula Weight: 429.38
• Synonym: 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol dihydrochloride

Specifications

• Chemical Name or Material: ZK 756326
• CAS: 874911-96-3
• Molecular Formula: C₂₁H₂₈N₂O₃·2HCl
• Synonym: 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol dihydrochloride

• Quantity: 50mg
• Purity Grade: >99%
• Formula Weight: 429.38