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ZK 200775, Tocris Bioscience™

Competitive AMPA/kainate antagonist

Brand:  Tocris (Bio-Techne) 234550

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13461074

  • £684.77 / 50mg


Estimated Shipment
03-09-2018
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Description

Description

Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (Ki = 120 nM) and [3H]-CNQX (Ki = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC50 values range from 2.5 to 11 μM). Inhibits currents induced by AMPA, kainate and NMDA with IC50 values of 21 nM, 27 nM, and > 1 μM respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo.
Specifications

Chemical Identifiers

161605-73-8
409.258
[[3, 4-Dihydro-7-(4-morpholinyl)-2, 3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid
C14H15F3N3O6P
WZMQMKNCWDCCMT-UHFFFAOYSA-N
208953

Specifications

ZK 200775
161605-73-8
C14H15F3N3O6P
WZMQMKNCWDCCMT-UHFFFAOYSA-N
[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]methylphosphonic acid
208953
50mg
>99%
[[3, 4-Dihydro-7-(4-morpholinyl)-2, 3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid
C1COCCN1C2=CC3=C(C=C2C(F)(F)F)NC(=O)C(=O)N3CP(=O)(O)O
409.258
409.25
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